iCAGES Documentation

iCAGES is an efficient software tool to prioritizes personalized cancer driver mutations, genes and drugs. Given input in ANNOVAR input format, VCF format or BED format, iCAGES can generate a list of

  • iCAGES mutation scores for all point coding variants, non-coding variants and structural variations, which measure genomic cancer driving potential of these variants.

  • iCAGES gene scores for all mutated genes, which measure personal cancer driving potential of these genes.

  • iCAGES drug scores for all potential drugs targeting any gene mutated in this particular patient.

Please click the menu items to navigate through this website. Check here to see the web interface of iCAGES. To recieve program updates, please use the iCAGES mailing list. If you have questions, comments and bug reports, please post them in the Disqus comment form in this website (or email me coco90417@gmail.com or my mentor Dr. Kai Wang kaichop@gmail.com directly). Thank you very much for your help and support!


new 2015Feb26: v1.0.0 initial stable release of iCAGES command line is available now!

new 2015Nov27: v1.0.1 stable release of iCAGES command line is available now!

new 2017Jan08: v1.0.2 stable release of iCAGES command line is available now!